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ea0092op-12-01 | Oral Session 12: Emerging Insights into Thyroid Cancer Genetics | ETA2023

Prospective evaluation of thyrospec molecular testing of indeterminate thyroid nodule cytologies following diagnostic pathway optimization

Stewardson Paul , Eszlinger Markus , Wu Jiahui , Khalil Moosa , J Demetrick Douglas , Cheung Winson , Box Adrian , Paschke Ralf

Objectives: Molecular diagnostic tests for indeterminate thyroid nodules (ITNs) are marketed based on negative predictive value (NPV) and benign call rate. Arguments that unnecessary surgeries are avoided based on NPV/BCR incorrectly assume that all ITNs would undergo diagnostic surgery in the absence of molecular testing. In our practice with centralized triage and cytopathology the resection and malignancy rate, respectively, were 21% and 26% for AUS/FLUS and 56% and 43% for...

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ea0084op-09-46 | Oral Session 9: Thyroid Cancer Clinical | ETA2022

Interim outcome analysis of prospective ATA recurrence risk (RR) stratification for postoperative treatment and follow up of differentiated thyroid cancer (DTC)

Wu Jiahui , Yang Hu Xun , Ghaznavi Sana , Kinnear Susan , Symonds Christopher , Grundy Peter , Parkins Vicky , Sharma Priyanka , Lamb Debbie , Khalil Moosa , Hyrcza Martin , Chandarana Shamir , Pasieka Janice , Harvey Adrian , Warshawski Joseph , Hart Robert , Deutschman Michael , Randall Derrick , Paschke Ralf

Objective: The 2016 ATA RR assessment recommendations for patients with DTC were based on retrospective studies. We present the first outcomes of a prospective assessment of thyroid cancer management according to the ATA RR stratification.Methods: Using the Calgary prospective thyroid cancer database, we identified 612 patients with differentiated thyroid cancer (DTC) treated at our centre between April 2017 and December 2021. Each case was reviewed by t...

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Endocrine Abstracts

Prospective evaluation of thyrospec molecular testing of indeterminate thyroid nodule cytologies following diagnostic pathway optimization

Interim outcome analysis of prospective ATA recurrence risk (RR) stratification for postoperative treatment and follow up of differentiated thyroid cancer (DTC)

BiosciAbstracts